We’ve all heard about “Long COVID,” but what is it?   “Long COVID” is a term used to describe the ongoing symptoms experienced by people who have been infected with the SARS-CoV-2 virus, which causes COVID-19.  Common symptoms include fatigue, shortness of breath, headaches, problems concentrating, muscle aches, and joint pain—all of which can last weeks or even months after the initial infection.

These symptoms can range from mild to severe.  While it isn’t clear exactly how many people are affected by Long Covid, estimates suggest that up to 10% of those who had a mild case may still be experiencing symptoms several months later.

The exact cause of Long Covid is still unclear, but some researchers believe that it may be an autoimmune condition. In this blog post, we’ll explore the evidence to determine whether this is true.

Could Long Covid Be An Autoimmune Condition

Maybe…. One theory suggests that this condition could be caused by an autoimmune reaction triggered by the virus itself. Autoimmune reactions occur when the body’s immune system mistakenly attacks its own cells and tissues instead of fighting off foreign invaders like viruses or bacteria.

Such reactions can cause chronic inflammation and even organ damage if left untreated for too long.  This means that it’s important to identify potential triggers for autoimmune reactions early on so that they can be treated effectively before any permanent damage occurs.

There is anecdotal evidence from those who have experienced long COVID and report feeling worse after exposure to certain substances such as pollen or smoke—both of which can trigger inflammation in those with autoimmune conditions. Additionally, research has shown that antibodies produced during infection with SARS-CoV-2 can cause inflammation and tissue damage in some people, indicating that their bodies are mounting an immune response against themselves.

It’s important to consider genetics when discussing Long Covid—specifically, genes related to autoimmune disorders such as lupus and rheumatoid arthritis. Studies have suggested that certain genetic variants can predispose individuals to increased risk of developing autoimmune conditions—and this same concept may apply to those with Long Covid as well. In other words, if you already have a genetic predisposition towards autoimmunity, you may be more likely than others to experience longer-lasting effects from COVID-19 infection.

Finally, there have been reports of patients experiencing more severe long COVID symptoms if they already had an existing autoimmune condition prior to being infected with SARS-CoV-2.   For example, some research has suggested that people with underlying health conditions such as diabetes or lupus may be at a higher risk for developing Long COVID than those without such conditions.

Furthermore, certain treatments used to manage autoimmune conditions have been shown to improve long-term Covid-19 symptoms in some patients—indicating a potential link between autoimmunity and Long Covid. Taken together, these pieces of evidence indicate that long COVID could indeed be an autoimmune condition in some cases.


With so much still unknown about both Covid-19 and autoimmunity it can often feel overwhelming trying to stay informed about potential risks associated with them both individually let alone when combined together in the form of Long Covid!

At present, it remains unclear if long COVID is caused by autoimmunity or another underlying factor such as lingering viral particles or dysregulation of the immune system due to stress or other environmental factors. Research into this area is ongoing and further studies will help us gain a better understanding of why some people experience longer lasting symptoms after recovering from a SARS-CoV-2 infection than others do.

For now, though, it appears that there is evidence suggesting that autoimmunity may play a role in some cases of long COVID—particularly in those who have existing autoimmune conditions prior to infection—and so further investigation into this potential link is warranted.

It’s important to remember that while research on this subject is ongoing and no definitive answer has yet been reached regarding whether long Covid is indeed caused by autoimmunity, it’s best not to take any chances and seek out medical advice if you think your health may be at risk due to any type of autoimmunity issue related to Covid-19 infection.  This is especially true for women over 40 due to their unique vulnerability and susceptibility factors associated with age and gender issues.

Are you experiencing long COVID?  Leave a comment and let me know.


***Disclaimer: This post is for informational purposes only and should not be construed as medical advice***



  • Susan Taylor, RDN LD

    Meet Susan, registered dietitian / nutritionist and fellow autoimmune warrior who is dedicated to helping women with autoimmune disease get their groove back. With the right diet and lifestyle changes, Susan empowers her clients to take control of their health and feel their best. When she's not busy saving the world you can find Susan strolling along the beach, jet-setting to new destinations, and soaking up quality time with family & friends.

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